Acyl bromides
Selleck Chemical LLC Butylscopolamine Bromide S2378-25mg
Butylscopolamine Bromide (Scopolamine Butylbromide (-)-Scopolamine butylbromide Hyoscine butylbromide) is a peripherally acting antimuscarinic anticholinergic agent used as an abdominal-specific antispasmodic
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-10mM/1mL
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-25mg
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Selleck Chemical LLC Domiphen Bromide S4186-50mg
Domiphen bromide (NSC-39415) is a quaternary ammonium antiseptic with actions as a cationic surfactant
Selleck Chemical LLC Umeclidinium bromide S3735-5mg
Umeclidinium bromide(GSK573719A) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD)
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 10g
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 and BRD4 (IC50s 0.08 0.05 and 0.02 UM respectively) and is selective for BD2 over BD1 (IC50s 3.76 2.34 and 1.16 UM for BRD2 BRD3 and BRD4 respectively) as well as CREBBP and p300 (IC50s 50 UM for both) decreases levels of the mRNAs encoding IL-6 and VCAM-1 in primary synovial fibroblasts isolated from patients with rheumatoid arthritis at 10 and 30 UM It prevents LPS-induced increases in IL-6 and Ifn-Y serum levels in a mouse model of LPS-induced endotoxemia at 75 mg/kg inhibits collagen-induced increases in ankle and knee diameter cartilage damage the ankle tissue levels of mRNAs encoding IL-1B Mmp-3 Mmp-13 and Rankl and ankle joint protein levels of IL-6 and VCAM-1 in a rat model of collagen-induced rheumatoid arthritis at 25 50 and 75 mg/kg twice per day improves gait and mobility and reverses body w8 loss as well as decreases the number of spinal cord inflammatory foci and apoptotic cells
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 25g
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 and BRD4 (IC50s 0.08 0.05 and 0.02 UM respectively) and is selective for BD2 over BD1 (IC50s 3.76 2.34 and 1.16 UM for BRD2 BRD3 and BRD4 respectively) as well as CREBBP and p300 (IC50s 50 UM for both) decreases levels of the mRNAs encoding IL-6 and VCAM-1 in primary synovial fibroblasts isolated from patients with rheumatoid arthritis at 10 and 30 UM It prevents LPS-induced increases in IL-6 and Ifn-Y serum levels in a mouse model of LPS-induced endotoxemia at 75 mg/kg inhibits collagen-induced increases in ankle and knee diameter cartilage damage the ankle tissue levels of mRNAs encoding IL-1B Mmp-3 Mmp-13 and Rankl and ankle joint protein levels of IL-6 and VCAM-1 in a rat model of collagen-induced rheumatoid arthritis at 25 50 and 75 mg/kg twice per day improves gait and mobility and reverses body w8 loss as well as decreases the number of spinal cord inflammatory foci and apoptotic cells
TARGETMOL CHEMICALS INC KRN2 BROMIDE 5MG
Also available in 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. KRN2 bromide is a potent selective inhibitor of nuclear factor of activated T cells (NFAT5 IC50= 0.1 μM). purity: 99%
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
AdipoGen 3-ITCEt-BPO-pyridinium bromide
Chemical. CAS 155863-02-8. Formula C20H18BrN3O2S. MW 444.34. Synthetic. Class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Relatively low extinction coefficient Epsilon∼ >20,000 in EtOH.
AdipoGen 4-ITCB-MPO-pyridinium bromide
Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
TARGETMOL CHEMICALS INC DEMECARIUM BROMIDE 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Demecarium bromide (BC-48) is a potent cholinesterase inhibitorand is treatment glaucoma agent. purity: 98%
TARGETMOL CHEMICALS INC UMECLIDINIUM BROMIDE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist. purity: 99%